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Yes, there are specific dosage restrictions for Lipitor (atorvastatin) in elderly patients. The recommended starting dose for adults, including elderly patients, is 10-20 mg once daily, which may be adjusted based on the patient's response and individual needs [1]. However, for patients with a high risk of muscle adverse effects, including those with advanced age, a starting dose of 10 mg or less is recommended [1].
Additionally, the FDA recommends a starting dose of 10-20 mg once daily for patients with renal impairment, and a starting dose of 10 mg once daily for patients taking strong CYP3A4 inhibitors, such as certain antifungal and antiviral medications [1].
It is important to note that the dosage of Lipitor may need to be adjusted based on the patient's individual needs and response, and regular monitoring of liver function and muscle enzymes is recommended [1].
In summary, while the starting dosage for Lipitor in elderly patients is generally the same as for other adults, a lower starting dose may be recommended for patients at a high risk of muscle adverse effects, including those with advanced age.
Sources:
[1] "Lipitor (atorvastatin) tablets, for oral use." U.S. Food and Drug Administration. <
https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/202677s043lbl.pdf>.