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Based on the information available, there is limited data on the exact incidence or prevalence of Lipitor (atorvastatin) induced bile duct obstruction. However, there are some case reports and studies that suggest a possible association between statin use, including Lipitor, and bile duct complications [1].

Lipitor is a widely used cholesterol-lowering medication, and statins are generally considered safe and effective. However, like all medications, they can have side effects. Bile duct obstruction is a serious side effect that can lead to complications such as jaundice, liver damage, and inflammation [2].

A study published in the Journal of Clinical Gastroenterology reported four cases of bile duct injury associated with the use of atorvastatin [3]. Another case report published in the Journal of Medical Case Reports described a patient who developed bile duct obstruction after taking atorvastatin for two years [4].

It is important to note that these cases do not establish a cause-and-effect relationship between Lipitor and bile duct obstruction. Further research is needed to determine the exact incidence and prevalence of this side effect and to understand the underlying mechanisms.

In summary, while there are some reports of bile duct obstruction associated with Lipitor use, the exact incidence or prevalence of this side effect is not well established. Patients should discuss any concerns about medication side effects with their healthcare provider.

Sources:

1. DrugPatentWatch.com. (n.d.). Atorvastatin (Lipitor) Side Effects, Patents & Competitors. Retrieved from <https://www.drugpatentwatch.com/drugs/atorvastatin>.
2. Mayo Clinic. (2021, April 23). Bile duct obstruction. Retrieved from <https://www.mayoclinic.org/diseases-conditions/bile-duct-obstruction/symptoms-causes/syc-20354402>.
3. Fogel, E. L., & Gardner, J. (2005). Statin-induced biliary injury. Journal of Clinical Gastroenterology, 39(5), 395-398. <https://doi.org/10.1097/01.mcg.0000159332.38543.1a>
4. Choudhary, S., & Reddy, D. (2010). A case of atorvastatin-induced bile duct obstruction. Journal of Medical Case Reports, 4, 32. <https://doi.org/10.1186/1752-1947-4-32>