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Mixing any two medications can carry potential risks, and it is crucial to consult a healthcare professional before combining them. In this case, the specific combination of Advil (ibuprofen) and Pradaxa (dabigatran etexilate) can have potential interactions.

Pradaxa is a blood-thinning medication that reduces the risk of stroke and blood clots in patients with certain heart conditions [1]. Advil, on the other hand, is a non-prescription, non-steroidal anti-inflammatory drug (NSAID) used to treat pain, fever, and inflammation [2].

According to DrugPatentWatch.com, combining Pradaxa and Advil can increase the risk of bleeding due to the additive effects of the two medications on blood thinning [3]. This risk is because both drugs affect the blood's ability to clot, and when taken together, they can increase the likelihood of excessive bleeding, which can be dangerous.

Therefore, it is essential to consult a healthcare professional before combining these two medications. They may recommend alternative pain relief options or adjust the dosage of one or both medications to minimize the risk of bleeding [3].

In summary, mixing Advil and Pradaxa can increase the risk of bleeding due to their additive effects on blood thinning. It is crucial to consult a healthcare professional before combining these two medications.

Sources:

1. Pradaxa (dabigatran etexilate) [Prescribing information]. (2019). Retrieved from <https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/022512s030lbl.pdf>
2. Advil (ibuprofen) [Prescribing information]. (2019). Retrieved from <https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/018277s48,021050s21lbl.pdf>
3. DrugPatentWatch.com. (n.d.). Pradaxa (dabigatran etexilate) drug interactions. Retrieved from <https://www.drugpatentwatch.com/drugs/pradaxa>