See the DrugPatentWatch profile for lurbinectedin

I could not find specific information on the typical lurbinectedin dosage for infants. However, lurbinectedin is a drug that has been approved by the US Food and Drug Administration (FDA) for the treatment of metastatic small cell lung cancer (SCLC) in adults [1]. It is a type of medication called a selective inhibitor of netosis, which works by blocking the activity of an enzyme called neutrophil elastase [2].

According to the drug's prescribing information, the recommended dosage of lurbinectedin for adults is 3.2 mg/m2 administered as a 1-hour intravenous infusion every 21 days until disease progression or unacceptable toxicity [3]. The safety and effectiveness of lurbinectedin have not been established in pediatric patients [3].

It is important to note that the dosage of a medication can vary depending on several factors, such as the patient's age, weight, kidney and liver function, and other medications they may be taking [4]. Therefore, it is essential to consult with a healthcare provider for specific dosing information for each individual patient.

In summary, while there is no specific information available on the typical lurbinectedin dosage for infants, it is a medication approved for the treatment of metastatic SCLC in adults. The recommended dosage for adults is 3.2 mg/m2 administered as a 1-hour intravenous infusion every 21 days. The safety and effectiveness of lurbinectedin have not been established in pediatric patients.

Sources:

1. FDA approves new treatment for small cell lung cancer. US Food and Drug Administration. <https://www.fda.gov/drugs/resources-information-approved-drugs/fda-approves-new-treatment-small-cell-lung-cancer>.
2. Lurbinectedin. Drugs.com. <https://www.drugs.com/mtm/lurbinectedin.html>.
3. Zepzelca (lurbinectedin) prescribing information. EUSA Pharma (US), Inc. <https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/213537s000lbl.pdf>.
4. Medication dosage. Mayo Clinic. <https://www.mayoclinic.org/tests-procedures/medication-dosage/about/pac-20393530>.