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When using Lipitor, a statin medication used to lower cholesterol levels, liver function tests are generally not required on a regular basis. According to the prescribing information provided by the drug's manufacturer, Pfizer, routine monitoring of liver enzymes is typically not necessary during Lipitor therapy [1]. However, it is recommended to perform liver enzyme tests before initiating Lipitor treatment and as clinically indicated thereafter.

Liver enzymes that may be tested include alanine aminotransferase (ALT) and aspartate aminotransferase (AST). Elevated levels of these enzymes may indicate liver damage or inflammation. If elevated liver enzymes are detected, further evaluation is required, and Lipitor treatment should be temporarily withheld or discontinued [1].

It is important to note that Lipitor is generally well-tolerated, and liver problems are rare. However, patients with a history of liver disease or elevated liver enzymes should be closely monitored during Lipitor therapy [1].

In summary, liver tests, such as ALT and AST, may be required before starting Lipitor treatment and as clinically indicated thereafter. Routine monitoring of liver enzymes is typically not necessary during Lipitor therapy.

Sources:
[1] Pfizer. (2017). Lipitor (atorvastatin) Prescribing Information. Retrieved from <https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/202080s038lbl.pdf>
[2] DrugPatentWatch.com. (n.d.). Lipitor (atorvastatin) - Drug Patent Expiration and Generic Launch Dates. Retrieved from <https://www.drugpatentwatch.com/drugs/lipitor>