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Yes, Advil (ibuprofen) can have side effects that mimic certain depressive symptoms. According to Drugs.com, some of the less common side effects of Advil include anxiety, depression, and nervousness [1]. These symptoms are not typical of Advil use, but they can occur in some individuals.

It is important to note that Advil is a nonsteroidal anti-inflammatory drug (NSAID) that is commonly used to treat pain, fever, and inflammation. While Advil can have side effects that mimic depressive symptoms, it is not a commonly reported side effect.

If you are experiencing depressive symptoms while taking Advil, it is important to speak with your healthcare provider. They can help determine whether the symptoms are related to Advil use or if they are indicative of a separate underlying condition.

In summary, while Advil can have side effects that mimic certain depressive symptoms, it is not a common side effect. If you are experiencing depressive symptoms while taking Advil, it is important to speak with your healthcare provider.

Sources:
[1] <https://www.drugs.com/sfx/advil-side-effects.html>