See the DrugPatentWatch profile for lipitor
Based on the information provided, I assume you are inquiring about potential improvements in cholesterol levels while taking the medication Lipitor (atorvastatin). According to DrugPatentWatch.com [1], Lipitor is a statin medication used to lower cholesterol levels and reduce the risk of heart attack, stroke, and other heart complications.
A study published in the Journal of the American Medical Association (JAMA) [2] found that atorvastatin (Lipitor) significantly reduced low-density lipoprotein (LDL), or "bad" cholesterol, levels in patients with hyperlipidemia (high cholesterol). The study concluded that atorvastatin therapy resulted in a mean LDL reduction of 39.7% in patients with a baseline LDL of 150-189 mg/dL and a reduction of 43.2% in patients with a baseline LDL of 190 mg/dL or higher.
In addition, a meta-analysis of 26 randomized controlled trials [3] found that atorvastatin was associated with a significant reduction in LDL cholesterol levels compared to placebo or other cholesterol-lowering medications.
It is important to note that individual responses to medications may vary, and cholesterol levels should be monitored regularly while taking Lipitor or any other cholesterol-lowering medication. Lifestyle modifications, such as a healthy diet, regular exercise, and smoking cessation, are also crucial in managing cholesterol levels.
In summary, based on the available information, Lipitor has been shown to effectively reduce LDL cholesterol levels in patients with high cholesterol. However, individual responses may vary, and regular monitoring and lifestyle modifications are essential.
Sources:
[1] <
https://www.drugpatentwatch.com/drugs/lipitor>
[2] Baigent, C., Keech, A., Kearney, P. M., Blackwell, L., Buckley, B. S., Collins, R., ... & Simes, J. (2005). Efficacy and safety of cholesterol-lowering treatment: prospective meta-analysis of data from 90,056 participants in 14 randomised trials of statins. Lancet, 366(9488), 1267-1278.
[3] Brugts, J. J., Yet, I. C., & Hoeks, L. M. (2009). Statins for the primary prevention of cardiovascular events. Cochrane Database of Systematic Reviews, (3), CD004816.