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There is currently no scientific evidence to suggest that garlic supplements directly reduce the potency of Lipitor (atorvastatin), a medication used to treat high cholesterol levels. However, garlic has been studied for its potential cholesterol-lowering effects, which could potentially impact the effectiveness of Lipitor if used concurrently [1].

Garlic has been shown to have a modest effect on lowering total cholesterol and low-density lipoprotein (LDL, or "bad") cholesterol levels [1][2]. This may be due to garlic's ability to inhibit the synthesis of cholesterol in the body [1]. Nonetheless, the impact of garlic on cholesterol levels is generally mild when compared to cholesterol-lowering medications like Lipitor [1].

It is important to note that combining garlic supplements with Lipitor could potentially lead to additive effects on cholesterol reduction [1]. While this might seem beneficial, it could also increase the risk of side effects related to low cholesterol levels [1]. Moreover, potential interactions between garlic and Lipitor have not been extensively studied, and individual responses may vary [1].

If you are considering taking garlic supplements while on Lipitor, it is crucial to consult with a healthcare professional or pharmacist [1]. They can provide personalized advice based on your medical history, current medications, and potential interactions [1].

Sources:

1. DrugPatentWatch.com. (n.d.). Garlic and Atorvastatin (Lipitor) Interaction. Retrieved from https://drugpatentwatch.com/interactions/garlic-and-atorvastatin-lipitor
2. National Center for Complementary and Integrative Health. (2016, December). Garlic. Retrieved from https://www.nccih.nih.gov/health/garlic
3. Cleveland Clinic. (2020, September 24). Garlic: A Heart-Healthy Wonder Drug? Retrieved from https://health.clevelandclinic.org/is-garlic-a-heart-healthy-wonder-drug/