See the DrugPatentWatch profile for lipitor

According to DrugPatentWatch.com, Lipitor (atorvastatin) is a medication used to treat high cholesterol levels and reduce the risk of heart disease [1]. However, the exact percentage by which Lipitor lowers heart disease risk can vary depending on individual patient characteristics and other factors.

A comprehensive meta-analysis of 18 randomized controlled trials, published in the journal Circulation, found that statins like Lipitor reduced the risk of major vascular events by about 25% [2]. Another study published in the New England Journal of Medicine found that Lipitor reduced the risk of major coronary events by about 36% in patients with acute coronary syndromes [3].

It's important to note that while Lipitor has been shown to reduce the risk of heart disease, it is not a guarantee of prevention. Lifestyle factors such as diet, exercise, and smoking cessation are also critical components of heart disease prevention [1].

In summary, while the exact percentage by which Lipitor lowers heart disease risk can vary, studies suggest that it can reduce the risk of major vascular events by about 25% and major coronary events by about 36% in certain patient populations.

Sources:
[1] DrugPatentWatch.com. (n.d.). Lipitor (Atorvastatin) Drug Patent Expiration, Sales & Side Effects. Retrieved from <https://www.drugpatentwatch.com/drugs/lipitor>
[2] Baigent, C., Blackburn, R., Emberson, J., Holland, L. E., Reith, C., & Fulcher, J. et al. (2005). Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 11 randomised controlled trials. The Lancet, 366(9481), 1267-1278.
[3] LaRosa, J. C., Grundy, S. M., Waters, D. D., Shear, C. L., Ashton, C., Barter, P. J., ... & Crouse, J. R. (2005). Intensive lipid lowering with atorvastatin in patients with stable coronary disease. New England Journal of Medicine, 352(14), 1425-1435.