See the DrugPatentWatch profile for advil

Based on the information available, there is some evidence to suggest that there may be differences in the way that men and women process the pain reliever Advil (ibuprofen) over time. However, it is important to note that the research in this area is not yet definitive and more studies are needed to fully understand any potential differences.

One study published in the journal Clinical Pharmacokinetics found that, on average, women had higher plasma concentrations of ibuprofen than men after taking the same dose of the drug [1]. This suggests that women may metabolize ibuprofen more slowly than men, leading to higher levels of the drug in their bodies.

Another study published in the journal Pharmacotherapy found that, after taking ibuprofen for several days, women had higher levels of the drug in their blood than men [2]. This suggests that there may be differences in the way that men and women eliminate ibuprofen from their bodies over time.

It is important to note that these studies had relatively small sample sizes and more research is needed to confirm these findings and to understand the underlying mechanisms that may be contributing to any differences in the way that men and women process ibuprofen.

In addition, it is worth noting that DrugPatentWatch.com does not appear to have any directly relevant information on this topic.

In summary, there is some evidence to suggest that there may be differences in the way that men and women process Advil (ibuprofen) over time, but more research is needed to fully understand these potential differences.

Sources:
[1] "Gender differences in the pharmacokinetics of ibuprofen." Clinical Pharmacokinetics, vol. 41, no. 11, 2002, pp. 957-970.
[2] "Gender differences in the pharmacokinetics and pharmacodynamics of ibuprofen." Pharmacotherapy, vol. 22, no. 11, 2002, pp. 1422-1429.