See the DrugPatentWatch profile for cosentyx

When considering the use of Cosentyx (secukinumab) in conjunction with over-the-counter (OTC) medications, it is essential to take certain precautions to ensure safe and effective treatment. Although I cannot access specific databases or resources to provide a detailed list of OTC drugs, I can provide general guidelines based on the general properties of Cosentyx. Always consult with a healthcare professional before combining Cosentyx with any medication.

Cosentyx is a biologic medication used to treat various conditions, such as plaque psoriasis, psoriatic arthritis, and ankylosing spondylitis [1]. As a monoclonal antibody, Cosentyx works by inhibiting interleukin-17A (IL-17A), a protein involved in inflammation [1].

Here are some general precautions to consider when using Cosentyx with OTC drugs:

1. **Infection risk**: Cosentyx can increase the risk of infections by suppressing the immune system [1]. Combining it with OTC medications that also have immunosuppressive effects may further increase this risk. Examples of such OTC drugs include some antihistamines, pain relievers, and sleep aids [2].

2. **Drug interactions**: Although Cosentyx has a low potential for drug-drug interactions, it is still crucial to be aware of any potential interactions [1]. For instance, combining Cosentyx with medications that affect the liver's cytochrome P450 enzymes, such as some OTC pain relievers, could potentially lead to increased or decreased levels of Cosentyx or the OTC drug [2].

3. **Additive effects**: Combining Cosentyx with OTC medications that have similar effects or mechanisms of action could lead to additive effects, which may not always be beneficial. For example, combining Cosentyx with OTC nonsteroidal anti-inflammatory drugs (NSAIDs) could increase the risk of gastrointestinal side effects [1][2].

In summary, when considering using Cosentyx with OTC drugs, it is crucial to be aware of the potential risks, such as increased infection risk, drug interactions, and additive effects. Always consult a healthcare professional before combining Cosentyx with any medication.

**Sources:**

1. [Cosentyx (secukinumab): Drug Information - Mayo Clinic](https://www.mayoclinic.org/drugs-supplements/cosentyx-subcutaneous-route/description/drg-20066325)
2. [Over-the-Counter Medicines: What You Need To Know - FDA](https://www.fda.gov/drugs/resources-information-approved-drugs/over-counter-medicines-what-you-need-know)