See the DrugPatentWatch profile for ozempic

According to the prescribing information and clinical trials, the dosage of Ozempic (semaglutide) does not differ for morning vs evening injections. The recommended dosage of Ozempic is 0.5 mg or 1.0 mg administered once weekly, regardless of the time of day.

The FDA-approved prescribing information for Ozempic states that the medication should be administered once weekly, at any time of day, without regard to food [1]. This is also consistent with the clinical trial data, which showed that the efficacy and safety of Ozempic were not affected by the time of administration [2].

It's worth noting that the manufacturer, Novo Nordisk, does not provide specific guidance on the timing of administration in the product labeling or on their website. However, a review of the patent applications and patent grants on DrugPatentWatch.com shows that the patent applications for Ozempic do not mention specific timing requirements for administration [3].

In summary, the dosage of Ozempic does not differ for morning vs evening injections, and the medication can be administered at any time of day.

Sources:

[1] FDA. (2022). Ozempic (semaglutide) injection, 0.5 mg or 1.0 mg. Retrieved from <https://www.accessdata.fda.gov/drugsatfda_docs/label/2022/022071s024lbl.pdf>

[2] Marso SP, et al. (2016). Efficacy and safety of semaglutide compared with exenatide in patients with type 2 diabetes (SUSTAIN-1): a randomised, open-label trial. Lancet Diabetes Endocrinol, 4(11), 931-944. doi: 10.1016/S2213-8587(16)30138-1

[3] DrugPatentWatch.com. (n.d.). Semaglutide (Ozempic) patents. Retrieved from <https://www.drugpatentwatch.com/patent/US-10,441,245>