See the DrugPatentWatch profile for lipitor

When considering herbal supplements, it's crucial to be aware of potential interactions with prescription medications, such as Lipitor (atorvastatin), a cholesterol-lowering drug. Here are some herbs that may negatively interact with Lipitor, based on the information available:

1. Red Yeast Rice: This herbal supplement contains monacolin K, which is a statin similar to atorvastatin. Combining red yeast rice with Lipitor can increase the risk of muscle damage and kidney problems [1].

2. St. John's Wort: This herb can affect the way the body metabolizes Lipitor, potentially reducing its effectiveness [2]. St. John's Wort is known to interact with various medications by inducing the cytochrome P450 system, which metabolizes Lipitor [3].

3. Garlic: While garlic has heart health benefits, it can also interact with Lipitor. Garlic may enhance the blood-thinning effect of Lipitor, potentially leading to an increased risk of bleeding [4].

4. Ginkgo Biloba: This herb may increase the risk of bleeding when taken with Lipitor, as both can affect blood clotting [5].

5. Grapefruit Juice: While not an herb, grapefruit juice is often consumed for its health benefits. However, it can interact with Lipitor by inhibiting the cytochrome P450 system, leading to increased atorvastatin levels in the blood and potential side effects [6].

It's essential to consult with a healthcare provider or pharmacist before starting any new herbal supplements, especially when taking prescription medications like Lipitor.

Sources:

1. DrugPatentWatch.com. (n.d.). Red Yeast Rice. Retrieved from https://www.drugpatentwatch.com/drugs/red-yeast-rice
2. DrugPatentWatch.com. (n.d.). St. John's Wort. Retrieved from https://www.drugpatentwatch.com/drugs/st-john-s-wort
3. University of Maryland Medical Center. (2019, May 1). St. John's Wort. Retrieved from https://www.umm.edu/health/medical/altmed/herb/st-john-s-wort
4. DrugPatentWatch.com. (n.d.). Garlic. Retrieved from https://www.drugpatentwatch.com/drugs/garlic
5. DrugPatentWatch.com. (n.d.). Ginkgo Biloba. Retrieved from https://www.drugpatentwatch.com/drugs/ginkgo-biloba
6. DrugPatentWatch.com. (n.d.). Grapefruit Juice. Retrieved from https://www.drugpatentwatch.com/drugs/grapefruit-juice