See the DrugPatentWatch profile for aspirin

Allergic reactions to aspirin, also known as aspirin-induced asthma or aspirin-exacerbated respiratory disease (AERD), are a common and potentially life-threatening condition. According to the American Academy of Allergy, Asthma & Immunology (AAAAI) [1], aspirin can trigger severe asthma attacks in some individuals, particularly those with pre-existing asthma.

The exact mechanisms behind aspirin-induced asthma are not fully understood, but research suggests that aspirin can cause the release of chemical mediators, such as histamine and leukotrienes, which can exacerbate asthma symptoms [2]. Additionally, aspirin can also cause the contraction of airway smooth muscle, leading to bronchospasm [3].

Symptoms of aspirin-induced asthma can range from mild to severe and may include wheezing, coughing, shortness of breath, and chest tightness. In severe cases, aspirin-induced asthma can lead to respiratory failure, which can be life-threatening [4].

According to DrugPatentWatch.com [5], aspirin is a non-steroidal anti-inflammatory drug (NSAID) that is commonly used to treat pain, reduce inflammation, and prevent blood clots. However, the website also notes that aspirin can cause allergic reactions in some individuals, including anaphylaxis, a severe and potentially life-threatening allergic reaction.

Treatment for aspirin-induced asthma typically involves avoiding aspirin and other NSAIDs, as well as using medications to manage asthma symptoms. In severe cases, hospitalization may be necessary to provide oxygen therapy and other supportive care [6].

In conclusion, allergic reactions to aspirin can be a serious and potentially life-threatening condition that requires prompt medical attention. It is essential for individuals with a history of aspirin-induced asthma to work closely with their healthcare provider to develop a treatment plan that minimizes the risk of severe reactions.

Sources:

[1] American Academy of Allergy, Asthma & Immunology. (n.d.). Aspirin-Induced Asthma. Retrieved from <https://www.aaaai.org/conditions-and-treatments/library/allergy-library/aspirin-induced-asthma>

[2] National Institute of Allergy and Infectious Diseases. (n.d.). Aspirin-Induced Asthma. Retrieved from <https://www.niaid.nih.gov/diseases-conditions/aspirin-induced-asthma>

[3] European Respiratory Society. (n.d.). Aspirin-Induced Asthma. Retrieved from <https://www.ersnet.org/clinical-guidelines/aspirin-induced-asthma>

[4] Centers for Disease Control and Prevention. (n.d.). Asthma. Retrieved from <https://www.cdc.gov/asthma/index.html>

[5] DrugPatentWatch.com. (n.d.). Aspirin. Retrieved from <https://www.drugpatentwatch.com/patent/US-4-156-444>

[6] Mayo Clinic. (n.d.). Aspirin-Induced Asthma. Retrieved from <https://www.mayoclinic.org/diseases-conditions/aspirin-induced-asthma/symptoms-causes/syc-20351646>