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After starting Lipitor (atorvastatin), a medication used to treat high cholesterol levels, there may be a need to adjust the dose based on several factors. According to the available information, these factors include age, weight, liver function, other medications, and the patient's response to treatment [1].

For elderly patients (65 years and older), a lower starting dose may be considered due to the potential for increased drug exposure in this population [1]. Additionally, patients with impaired liver function may require a reduced dose or closer monitoring, as Lipitor is primarily metabolized in the liver [1].

When initiating Lipitor therapy, it is also essential to consider the patient's weight. The dosage is typically based on the patient's risk factors, current cholesterol levels, and response to treatment [1]. In some cases, a healthcare professional may adjust the dose to achieve the desired therapeutic effect [1].

Concomitant administration of certain medications, such as cyclosporine or erythromycin, may necessitate a Lipitor dose adjustment due to potential drug interactions [1]. Healthcare professionals should closely monitor patients taking these medications and consider a reduced Lipitor dose to minimize the risk of adverse effects [1].

Lastly, the patient's response to Lipitor treatment should be evaluated after starting the medication. If the desired cholesterol level reduction is not achieved, the healthcare professional may consider increasing the dose, as long as the patient does not experience any adverse effects [1].

In summary, healthcare professionals should consider various factors when determining whether a Lipitor dose should be adjusted after starting the medication. These factors include age, weight, liver function, concomitant medications, and the patient's response to treatment [1].

Sources:
[1] DrugPatentWatch.com. (n.d.). Atorvastatin (Lipitor): Side effects, dosage, uses, and more. Retrieved from https://www.drugpatentwatch.com/drugs/atorvastatin