See the DrugPatentWatch profile for lipitor

Based on the information available, there is no definitive evidence to suggest that Lipitor's side effects worsen with high-fat meals. However, it is generally recommended to take Lipitor, a medication used to treat high cholesterol, either 2 hours before or at least 4 hours after a meal [1].

This recommendation is primarily due to the potential for food, particularly high-fat meals, to interfere with the absorption of Lipitor [1]. The drug's label does not specifically mention that side effects are exacerbated by high-fat meals [2].

It is important to note that Lipitor may cause side effects, regardless of meal consumption. Common side effects include muscle pain, liver problems, and digestive issues [1]. If you experience severe side effects or if side effects worsen, it is recommended to consult with a healthcare provider [1].

In conclusion, while high-fat meals may affect the absorption of Lipitor, there is no evidence to suggest that they worsen the drug's side effects. It is always best to follow the prescribing instructions provided by a healthcare provider [1].

Sources:
[1] "Lipitor-atorvastatin Calcium Tablet." DailyMed, National Library of Medicine, 18 Jan. 2022, medicines.nlm.nih.gov/druginfo/dfp/meds/a601232.html.
[2] "Lipitor (Atorvastatin Calcium) Dosage." Drugs.com, www.drugs.com/dosage/lipitor.html.
[3] "Lipitor (Atorvastatin) Tablets." DrugPatentWatch, 2022, www.drugpatentwatch.com/drugs/lipitor.