See the DrugPatentWatch profile for advil

Yes, Advil (ibuprofen) can cause adverse reactions over time. Long-term use of Advil can lead to side effects such as stomach ulcers, bleeding, and kidney damage [1]. It can also increase the risk of heart attack and stroke, especially with high doses and prolonged use [1][2]. Moreover, Advil may interact with other medications, leading to further health complications [1]. It is essential to consult a healthcare professional before starting or continuing any medication, including Advil, and to follow the recommended dosage and duration [1].

Sources:
[1] DrugPatentWatch.com. (n.d.). Advil Side Effects Lawsuit. Retrieved from <https://www.drugpatentwatch.com/advil-side-effects-lawsuit/>
[2] Mayo Clinic. (2021, October 22). Ibuprofen (Oral Route) Side Effects. Retrieved from <https://www.mayoclinic.org/drugs-supplements/ibuprofen-oral-route/side-effects/drg-20069671?p=1>