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Keytruda Side Effects: When to Consult a Doctor

Pembrolizumab, marketed under the brand name Keytruda, is a revolutionary immunotherapy medication used to treat various types of cancer, including melanoma, lung cancer, and breast cancer. While Keytruda has shown impressive results in clinical trials, it's essential to be aware of its potential side effects. In this article, we'll explore the key Keytruda side effects that require a doctor's consultation.

What are the Common Side Effects of Keytruda?

Before we dive into the side effects that need a doctor's consultation, it's essential to understand the common side effects associated with Keytruda. According to the FDA-approved label, the most common side effects of Keytruda include:

* Fatigue
* Diarrhea
* Nausea
* Rash
* Itching
* Hives
* Fever
* Chills
* Headache
* Muscle or bone pain

Side Effects That Require a Doctor's Consultation

While the common side effects listed above may be manageable with medication or lifestyle changes, some side effects of Keytruda require immediate medical attention. Here are some key side effects that need a doctor's consultation:

Severe Allergic Reactions

Keytruda can cause severe allergic reactions, including:

* Hives
* Swelling of the face, lips, tongue, or throat
* Difficulty breathing
* Dizziness or fainting

If you experience any of these symptoms, seek medical attention immediately.

Severe Infusion Reactions

Infusion reactions are a common side effect of Keytruda, but severe reactions can occur. Symptoms include:

* Fever
* Chills
* Nausea
* Vomiting
* Headache
* Muscle or bone pain
* Swelling of the face, lips, tongue, or throat

If you experience any of these symptoms, seek medical attention immediately.

Pneumonitis

Pneumonitis is a rare but life-threatening side effect of Keytruda. Symptoms include:

* Coughing
* Chest pain
* Shortness of breath
* Fever
* Chills

If you experience any of these symptoms, seek medical attention immediately.

Colitis

Colitis is a rare but serious side effect of Keytruda. Symptoms include:

* Diarrhea
* Abdominal pain
* Blood in the stool
* Fever

If you experience any of these symptoms, seek medical attention immediately.

Hepatitis

Hepatitis is a rare but serious side effect of Keytruda. Symptoms include:

* Fatigue
* Loss of appetite
* Nausea
* Vomiting
* Yellowing of the skin and eyes

If you experience any of these symptoms, seek medical attention immediately.

When to Consult a Doctor

If you're experiencing any of the side effects listed above, it's essential to consult your doctor immediately. Additionally, if you're experiencing any of the following symptoms, seek medical attention:

* Fever above 102°F (39°C)
* Severe headache or stiff neck
* Severe muscle or bone pain
* Severe rash or itching
* Difficulty breathing
* Swelling of the face, lips, tongue, or throat

Conclusion

Keytruda is a powerful immunotherapy medication that has shown impressive results in clinical trials. While it's essential to be aware of its potential side effects, it's crucial to consult a doctor if you're experiencing any severe or life-threatening symptoms. Remember, early detection and treatment can significantly improve outcomes.

Frequently Asked Questions

1. What are the most common side effects of Keytruda?

The most common side effects of Keytruda include fatigue, diarrhea, nausea, rash, itching, hives, fever, chills, headache, and muscle or bone pain.

2. What are the severe side effects of Keytruda that require a doctor's consultation?

Severe allergic reactions, severe infusion reactions, pneumonitis, colitis, and hepatitis are the severe side effects of Keytruda that require a doctor's consultation.

3. What should I do if I experience a severe side effect of Keytruda?

If you experience a severe side effect of Keytruda, seek medical attention immediately. Call your doctor or emergency services, and be prepared to provide information about your medication and any symptoms you're experiencing.

4. Can I continue taking Keytruda if I experience side effects?

It's essential to consult your doctor if you're experiencing side effects. Your doctor may recommend adjusting your dosage or switching to a different medication.

5. How can I reduce the risk of side effects when taking Keytruda?

To reduce the risk of side effects when taking Keytruda, it's essential to follow your doctor's instructions carefully, attend all scheduled appointments, and report any symptoms or concerns to your doctor immediately.

Sources:

1. Keytruda Prescribing Information. (2022). Retrieved from <https://www.merck.com/product/usa/picirculars/k/keytruda/keytrudapi.pdf>
2. DrugPatentWatch.com. (2022). Pembrolizumab (Keytruda) Patent Expiration. Retrieved from <https://www.drugpatentwatch.com/patent-expiration-date/pembrolizumab-keytruda>
3. National Cancer Institute. (2022). Pembrolizumab. Retrieved from <https://www.cancer.gov/about-cancer/treatment/types/immunotherapy/pembrolizumab-fact-sheet>
4. FDA. (2022). Pembrolizumab (Keytruda) FDA Approval. Retrieved from <https://www.fda.gov/drugs/drug-approvals-and-databases/pembrolizumab-keytruda-fda-approval>