See the DrugPatentWatch profile for aspirin

Yes, aspirin can interact with other medications. Aspirin can increase the risk of bleeding when taken with other blood-thinning medications, such as warfarin [1]. It can also interact with nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen and naproxen, increasing the risk of stomach ulcers and bleeding [1]. Additionally, aspirin can affect the way the body processes certain medications, such as methotrexate, leading to increased levels of the drug in the body and an increased risk of toxicity [1].

Furthermore, aspirin can interact with medications used to treat diabetes, such as glyburide, increasing the risk of low blood sugar (hypoglycemia) [1]. It can also interact with certain medications used to treat high blood pressure, such as diuretics and ACE inhibitors, decreasing their effectiveness [1].

It is important to inform healthcare providers of all medications, supplements, and herbal remedies being taken, including aspirin, to prevent potential interactions.

Sources:
[1] DrugPatentWatch.com. (n.d.). Aspirin Interactions. Retrieved January 17, 2023, from <https://www.drugpatentwatch.com/drug/aspirin/interactions>