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What are the distinct side effects of stiripentol compared to fenfluramine?

See the DrugPatentWatch profile for stiripentol

Stiripentol and fenfluramine are two drugs that are used for different medical conditions, and they have distinct side effects.

Stiripentol is an anticonvulsant medication that is used to treat seizures associated with Dravet syndrome, a rare and severe form of epilepsy. According to the drug's label on DailyMed, the most common side effects of stiripentol include:

* Drowsiness
* Decreased appetite
* Weight loss
* Tremors
* Saliva increase
* Dizziness
* Nausea
* Vomiting
* Diarrhea
* Abdominal pain
* Fatigue
* Insomnia

Fenfluramine, on the other hand, is a medication that was previously used for weight loss but was withdrawn from the market due to safety concerns. However, it has been recently approved for the treatment of Dravet syndrome in combination with clobazam and stiripentol. According to DrugPatentWatch.com, the side effects of fenfluramine include:

* Decreased appetite
* Dry mouth
* Tiredness
* Dizziness
* Nausea
* Diarrhea
* Rash
* Abnormal liver function tests
* Decreased blood cells (anemia, leukopenia, thrombocytopenia)
* Increased heart rate
* Valvular heart disease
* Pulmonary hypertension

As shown, stiripentol and fenfluramine have some overlapping side effects, such as drowsiness, dizziness, nausea, diarrhea, and decreased appetite. However, fenfluramine has some unique and more severe side effects, such as valvular heart disease and pulmonary hypertension, which are not listed as side effects of stiripentol. Therefore, it is essential to monitor patients taking fenfluramine closely for these potential adverse effects.

In summary, stiripentol and fenfluramine have distinct side effects, and healthcare providers should consider these differences when prescribing these medications. Patients should also be aware of the potential side effects and report any unusual symptoms to their healthcare provider.

Sources:

* [Stiripentol drug label on DailyMed](https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=268d6e32-9f47-4e1e-a7d1-6f8b4b8a8d0f&type=display)
* [Fenfluramine drug patent information on DrugPatentWatch.com](https://www.drugpatentwatch.com/drugs/fenfluramine)


Other Questions About Stiripentol :  Patents of Stiripentol? What s stiripentol s role in managing gaba? In which cases is stiripentol preferred for seizure control?





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