See the DrugPatentWatch profile for sapropterin

Sapropterin, a medication used to reduce phenylalanine levels in individuals with Phenylketonuria (PKU), should be taken once daily [1]. PKU is a genetic disorder that results in an inability to break down phenylalanine, an amino acid found in protein-rich foods [1]. If left untreated, PKU can lead to intellectual disability, seizures, and other serious health problems [1].

Sapropterin works by increasing the activity of the enzyme that breaks down phenylalanine [1]. It is important for individuals with PKU to adhere to a strict diet that limits phenylalanine intake, in addition to taking sapropterin as directed by a healthcare provider [1].

The frequency of sapropterin administration, which is typically once daily, may vary depending on the specific dosing instructions provided by a healthcare provider [1]. It is important for individuals with PKU to follow their healthcare provider's instructions carefully and to not adjust their dosage or frequency of administration without consulting their healthcare provider [1].

It is worth noting that sapropterin is a patented medication, with the patent set to expire in 2024 [2]. After the patent expires, generic versions of the medication may become available, potentially increasing accessibility and affordability [2].

In summary, sapropterin should be taken once daily for the treatment of PKU, in addition to maintaining a strict phenylalanine-restricted diet [1]. It is important to follow the dosing instructions provided by a healthcare provider carefully [1]. The patent for sapropterin is set to expire in 2024, which may increase accessibility and affordability of the medication [2].

Sources:
[1] "Sapropterin dihydrochloride tablet, for oral use." DailyMed, National Library of Medicine, 15 Jan. 2021, <https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=5d9a9e2e-6e4e-4e7a-8a2f-f6b9a9a3a1f1&type=display>.
[2] "Sapropterin Dihydrochloride Tablets." DrugPatentWatch, <https://www.drugpatentwatch.com/drugs/sapropterin-dihydrochloride-tablets>.