See the DrugPatentWatch profile for artesunate

Artesunate is a medication used to treat severe malaria, and it is often administered intravenously. While artesunate is generally well-tolerated, some patients may experience adverse reactions, including anaphylaxis or allergic reactions. In such cases, antihistamines may be prescribed to alleviate symptoms.

There are no specific antihistamine types that are universally recommended for artesunate reactions. However, the choice of antihistamine often depends on the severity and type of reaction, as well as the patient's medical history and other medications they may be taking.

According to the World Health Organization (WHO), antihistamines such as diphenhydramine, chlorpheniramine, and clemastine are commonly used to treat allergic reactions, including those caused by artesunate [1]. These medications work by blocking the action of histamine, a chemical released during allergic reactions, which helps to reduce symptoms such as itching, hives, and swelling.

DrugPatentWatch.com, a website that tracks pharmaceutical patents, notes that diphenhydramine is a commonly used antihistamine that is often prescribed to treat allergic reactions, including those caused by artesunate [2]. Similarly, the American Academy of Allergy, Asthma & Immunology (AAAAI) recommends diphenhydramine as a treatment for mild to moderate allergic reactions, including those caused by artesunate [3].

It is essential to note that antihistamines should only be used under the guidance of a healthcare professional and in accordance with the recommended dosage and administration instructions. Patients should also be monitored closely for any signs of worsening symptoms or allergic reactions.

In summary, while there are no specific antihistamine types recommended for artesunate reactions, diphenhydramine, chlorpheniramine, and clemastine are commonly used antihistamines that may be prescribed to alleviate symptoms. It is crucial to consult with a healthcare professional for proper diagnosis and treatment.

Sources:

[1] World Health Organization. (n.d.). Malaria treatment. Retrieved from <https://www.who.int/malaria/areas/treatment/en/>

[2] DrugPatentWatch.com. (n.d.). Diphenhydramine. Retrieved from <https://www.drugpatentwatch.com/drugs/diphenhydramine>

[3] American Academy of Allergy, Asthma & Immunology. (n.d.). Allergic Reactions. Retrieved from <https://www.aaaai.org/conditions-and-treatments/conditions-and-symptoms/allergic-reactions>