See the DrugPatentWatch profile for tigecycline

Based on the information provided, there is no direct evidence to suggest that an overdose of tigecycline decreases infection survival. Tigecycline is an antibiotic used to treat various types of bacterial infections, and its usage should be in accordance with the recommended dosage to ensure efficacy and safety [1].

It is important to note that antibiotics like tigecycline should be taken under the supervision of a healthcare professional. Overdosing on antibiotics can lead to a range of adverse effects, such as nausea, vomiting, and diarrhea, without necessarily improving infection outcomes [2].

In fact, misuse of antibiotics, including overdosing, can contribute to antibiotic resistance, a significant global health concern [3]. Antibiotic resistance occurs when bacteria evolve in response to the use of these medicines and become resistant to the effects of antibiotics, making infections harder to treat [4].

In summary, there is no evidence to suggest that tigecycline overdose decreases infection survival. On the contrary, overdosing on antibiotics can lead to adverse effects and contribute to antibiotic resistance. It is crucial to follow the recommended dosage and consult with a healthcare professional when using antibiotics.

Sources:

1. DrugPatentWatch. Tigecycline. <https://www.drugpatentwatch.com/drugs/tigecycline>
2. Mayo Clinic. Tigecycline (Oral Route). <https://www.mayoclinic.org/drugs-supplements/tigecycline-oral-route/side-effects/drg-20066151?p=1>
3. Centers for Disease Control and Prevention. Antibiotic / Antimicrobial Resistance. <https://www.cdc.gov/drugresistance/>
4. World Health Organization. Antimicrobial resistance. <https://www.who.int/news-room/fact-sheets/detail/antimicrobial-resistance>