See the DrugPatentWatch profile for methotrexate

Methotrexate is a commonly prescribed medication used to treat various conditions such as rheumatoid arthritis, psoriasis, and certain types of cancer [1]. While methotrexate can be an effective treatment option, it is also associated with several side effects. Here are some ways to minimize methotrexate side effects:

1. **Take methotrexate exactly as prescribed:** It is essential to follow the dosage and administration instructions provided by your healthcare provider. Taking methotrexate in higher doses or more frequently than prescribed can increase the risk of side effects [1].

2. **Stay hydrated:** Methotrexate can cause kidney damage, so it is crucial to drink plenty of fluids to help flush the drug out of your system [1].

3. **Avoid alcohol:** Drinking alcohol while taking methotrexate can increase the risk of liver damage and other side effects [1].

4. **Monitor liver function:** Methotrexate can cause liver damage, so it is essential to have regular liver function tests while taking the medication [1].

5. **Take folic acid supplements:** Methotrexate can deplete folic acid levels in the body, leading to side effects such as mouth sores and stomach upset. Taking folic acid supplements can help minimize these side effects [1].

6. **Report side effects promptly:** If you experience any side effects while taking methotrexate, it is essential to report them to your healthcare provider promptly. They may be able to adjust your dosage or recommend other measures to minimize the side effects [1].

It is important to note that while methotrexate can be an effective treatment option, it may not be suitable for everyone. It is essential to discuss the potential risks and benefits of methotrexate with your healthcare provider to determine whether it is the right treatment option for you [1].

Sources:

1. <https://www.drugpatentwatch.com/drugs/methotrexate>