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Based on the information available, there is no direct evidence suggesting that Lipitor (atorvastatin) directly increases the risk of liver damage. However, like other statins, Lipitor can increase liver enzyme levels, which is often used as a marker for liver damage [1].

An increase in liver enzymes does not necessarily mean that the liver has been damaged, but it can indicate inflammation or other issues with the liver [1]. If liver enzyme levels become significantly elevated while taking Lipitor, a healthcare provider may recommend discontinuing the medication or reducing the dosage [1].

It is important to note that Lipitor is generally safe and well-tolerated, and the benefits of taking the medication to lower cholesterol and reduce the risk of heart disease often outweigh the potential risks [1].

However, certain medications can interact with Lipitor and increase the risk of liver damage. For example, combining Lipitor with cyclosporine can increase the risk of liver damage [2]. Therefore, it is essential to inform a healthcare provider of all medications being taken, including over-the-counter drugs, supplements, and herbal remedies [1].

In summary, while Lipitor can increase liver enzyme levels, there is no direct evidence suggesting that it increases the risk of liver damage. However, certain medications can interact with Lipitor and increase the risk of liver damage, so it is essential to inform a healthcare provider of all medications being taken.

Sources:

1. Mayo Clinic. (2021). Atorvastatin (Oral Route) - Mayo Clinic. Mayo Clinic. <https://www.mayoclinic.org/drugs-supplements/atorvastatin-oral-route/side-effects/drg-20069050>.
2. DrugPatentWatch. (2021). Atorvastatin (Lipitor) Drug Interactions. DrugPatentWatch. <https://www.drugpatentwatch.com/drugs/atorvastatin-lipitor/interactions>.