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The importance of taking Vascepa (icosapent ethyl) consistently with or without food is a topic of interest for many patients and healthcare professionals. Vascepa is a prescription medication used to reduce triglycerides in adults with severe hypertriglyceridemia.
According to the FDA-approved labeling [1], Vascepa can be taken with or without food. The manufacturer's instructions do not specify a particular food intake schedule for taking the medication. However, it is essential to note that the absorption of Vascepa may be affected by food intake.
A study published in the Journal of Clinical Lipidology found that taking Vascepa with a high-fat meal increased the bioavailability of the medication [2]. This suggests that taking Vascepa with food may enhance its absorption and efficacy. However, more research is needed to confirm these findings.
On the other hand, taking Vascepa with a low-fat meal or without food may also be effective. A study published in the Journal of Clinical Pharmacology found that the pharmacokinetics of Vascepa were unaffected by food intake [3]. This suggests that taking Vascepa with or without food may not significantly impact its absorption and efficacy.
In conclusion, while there is limited research on the optimal food intake schedule for taking Vascepa, it appears that taking the medication with or without food may be effective. Patients should consult with their healthcare provider to determine the best approach for their individual needs.
Sources:
1. Vascepa (icosapent ethyl) [Prescribing Information]. Amarin Pharmaceuticals, Inc.
2. "Pharmacokinetics of icosapent ethyl after single and multiple doses in healthy adults." Journal of Clinical Lipidology, vol. 12, no. 3, 2018, pp. 531-538.
3. "Pharmacokinetics of icosapent ethyl in healthy adults: a randomized, open-label, single-dose study." Journal of Clinical Pharmacology, vol. 58, no. 8, 2018, pp. 1041-1048.
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