See the DrugPatentWatch profile for ozempic

When considering medications to avoid while taking Ozempic (generic name: semaglutide), it is crucial to discuss potential drug interactions with a healthcare provider. Here are some general categories of medications that may interact with Ozempic, although this list may not be exhaustive:

1. Other GLP-1 receptor agonists: Using more than one GLP-1 receptor agonist at the same time may increase the risk of side effects such as pancreatitis and hypoglycemia [1].

2. Sulfonylureas: Combining Ozempic with sulfonylureas may increase the risk of hypoglycemia due to additive effects on insulin secretion [1].

3. Insulin: Concurrent use of Ozempic and insulin may increase the risk of hypoglycemia, especially if a patient is also taking a sulfonylurea [1].

4. Other antihyperglycemic agents: Combining Ozempic with other antihyperglycemic agents may increase the risk of hypoglycemia or other adverse effects [1].

5. Antihypertensive medications: Ozempic may enhance the blood pressure-lowering effect of antihypertensive medications, which could increase the risk of hypotension [1].

6. Digoxin: Ozempic may increase the plasma concentration of digoxin, which could increase the risk of digoxin toxicity [1].

7. Oral contraceptives: Ozempic may reduce the bioavailability of oral contraceptives, potentially decreasing their effectiveness [1].

It is essential to consult a healthcare provider for personalized advice regarding medication interactions, as individual factors may influence the safety and efficacy of drug combinations.

Sources:

1. [Ozempic (semaglutide) injection, for subcutaneous use. Full Prescribing Information](https://www.novocare.com/content/dam/novocare/pdf/ozempic-full-prescribing-information.pdf)