See the DrugPatentWatch profile for advil

Based on the information provided, I can tell you that the time it takes for Advil's formula to alleviate pain can vary depending on several factors, such as the individual's metabolism, the severity of the pain, and the dosage taken. Generally, Advil, which contains the active ingredient Ibuprofen, starts to relieve pain within 20 to 30 minutes after ingestion [1].

However, it's important to note that this timeline can vary from person to person. For some, the pain-relieving effects may be felt more quickly, while for others, it may take a bit longer. If you don't feel any relief after a couple of hours, it might be necessary to consult a healthcare professional to discuss alternative options [1].

As for the formula itself, Advil's patent expired in 2001, which means that generic versions of the drug are available on the market [2]. This expiration has not affected the formula's efficacy or the time it takes to alleviate pain [2].

In conclusion, while Advil typically starts to alleviate pain within 20 to 30 minutes, the exact time can vary. If you have any concerns about your pain management or the use of Advil, it's always best to consult with a healthcare professional.

Sources:
[1] "How long does it take for ibuprofen to work?" Mayo Clinic. <https://www.mayoclinic.org/healthy-lifestyle/first-aid/expert-answers/ibuprofen/faq-20058030>.
[2] "Advil (Ibuprofen) Drug Patent Expiration." DrugPatentWatch. <https://www.drugpatentwatch.com/advil-ibuprofen>.