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There is limited scientific research directly investigating the impact of Advil, a brand name for the drug ibuprofen, on the benefits of antidepressant medications. Therefore, it is not possible to provide a definitive answer based on the available information.

However, it is important to note that both Advil and antidepressants can affect the gastrointestinal system, and concurrent use may increase the risk of gastrointestinal side effects [1].

Moreover, ibuprofen, like other non-steroidal anti-inflammatory drugs (NSAIDs), may interact with antidepressants, particularly selective serotonin reuptake inhibitors (SSRIs) and serotonin and norepinephrine reuptake inhibitors (SNRIs), leading to an increased risk of serotonin syndrome, a potentially life-threatening condition [2].

Therefore, it is crucial for individuals to consult with their healthcare providers before combining Advil with antidepressant medications. Healthcare providers can provide personalized advice based on an individual's health history, current medications, and other factors.

Sources:

1. "Ibuprofen." Mayo Clinic, Mayo Foundation for Medical Education and Research, 23 Jan. 2021, [www.mayoclinic.org/drugs-supplements/ibuprofen/side-effects/drg-20070863](http://www.mayoclinic.org/drugs-supplements/ibuprofen/side-effects/drg-20070863).
2. "Ibuprofen Interactions." RxList, [www.rxlist.com/ibuprofen-drug/patient-images-side-effects.htm#interactions](http://www.rxlist.com/ibuprofen-drug/patient-images-side-effects.htm#interactions).
3. "Ibuprofen." DrugPatentWatch, [www.drugpatentwatch.com/drugs/ibuprofen](http://www.drugpatentwatch.com/drugs/ibuprofen).