See the DrugPatentWatch profile for lipitor

Based on the information available, there are indeed alternatives to Lipitor (atorvastatin) that are known to have a lower impact on liver function.

Atorvastatin, the active ingredient in Lipitor, is a type of drug known as a statin, which reduces levels of cholesterol and other fats in the blood. However, some statins, including Lipitor, have been associated with elevations in liver enzymes, which can indicate liver damage [1].

Fortunately, there are other cholesterol-lowering medications that have a lower impact on liver function. These include:

1. Ezetimibe (Zetia): This medication works by blocking the absorption of cholesterol in the digestive tract, rather than affecting liver function [2].

2. Bile acid sequestrants: These medications, which include cholestyramine (Prevalite, Questran), colesevelam (Welchol), and colestipol (Colestid), work by binding to bile acids in the intestines and preventing their reabsorption. This can help lower cholesterol levels without affecting liver function [3].

3. PCSK9 inhibitors: These medications, which include alirocumab (Praluent) and evolocumab (Repatha), work by blocking a protein in the liver that helps regulate cholesterol levels. These medications have been shown to be effective in lowering cholesterol levels without affecting liver function [4].

It is important to note that while these medications may have a lower impact on liver function than Lipitor, they may still have other side effects and interactions with other medications. As such, it is important to speak with a healthcare provider before starting any new medication.

Sources:
[1] Mayo Clinic. (2021). Atorvastatin (Oral Route). Retrieved from <https://www.mayoclinic.org/drugs-supplements/atorvastatin-oral-route/side-effects/drg-20069055>
[2] National Library of Medicine. (2021). Ezetimibe. Retrieved from <https://medlineplus.gov/druginfo/meds/a605002.html>
[3] National Library of Medicine. (2021). Bile acid sequestrants. Retrieved from <https://medlineplus.gov/druginfo/meds/a601003.html>
[4] National Library of Medicine. (2021). PCSK9 inhibitors. Retrieved from <https://medlineplus.gov/druginfo/meds/a613028.html>
[5] DrugPatentWatch. (2021). Lipitor. Retrieved from <https://www.drugpatentwatch.com/drugs/lipitor>