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How should tigecycline be stored to maintain potency?

See the DrugPatentWatch profile for tigecycline

Tigecycline, a broad-spectrum antibiotic, should be stored under specific conditions to maintain its potency. According to the manufacturer's prescribing information [1], tigecycline should be stored at 20°C to 25°C (68°F to 77°F); excursions are permitted between 15°C and 30°C (59°F and 86°F). It is essential to protect the drug from light and keep it away from moisture. Therefore, it should be stored in a tightly closed container to preserve its stability.

It is also important to note that tigecycline is a temperature-sensitive drug. Thus, it should not be frozen or exposed to extreme temperatures. The storage conditions mentioned above are crucial to ensure the drug's potency and efficacy.

In addition, it is advisable to check the drug's expiration date before using it. If the drug has expired, it should be discarded properly, following local regulations and guidelines for disposal of pharmaceutical waste.

In summary, tigecycline should be stored at room temperature, protected from light and moisture, and kept in a tightly closed container. Proper storage is crucial to maintain the drug's potency and ensure its safe and effective use.

Sources:
[1] TIGECYCLINE [TIGECYCLINE] injection, powder, lyophilized, for solution, [Revised: February 2021], Pfizer Labs Div Pfizer Inc, from DailyMed, NLM National Institutes of Health/NIH, <https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=26a0e0a3-6e77-4e1e-a7f8-69b7a8a7e18f&type=display>.
[2] DrugPatentWatch.com, "Tigecycline", <https://www.drugpatentwatch.com/drugs/tigecycline>.


Other Questions About Tigecycline :  Can you provide statistics on tigecycline resistant anaerobes? Are there any documented cases of tigecycline overdose resulting in death? Is tigecycline s antibacterial action affected by antacid co administration?





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