See the DrugPatentWatch profile for lipitor

Based on the available information, Lipitor (atorvastatin) is generally considered safe for long-term use for lowering cholesterol levels and reducing the risk of cardiovascular disease [1][2]. However, its potential impact on liver function requires careful consideration.

According to the National Center for Biotechnology Information (NCBI), Lipitor is primarily metabolized in the liver, and its use can slightly increase liver enzymes [2]. Although this increase is usually not clinically significant, it is recommended to monitor liver function tests periodically during Lipitor therapy [2].

In rare cases, Lipitor may cause severe liver damage, including liver failure [3]. However, this side effect is not common and typically occurs in patients with pre-existing liver disease or those taking high doses of Lipitor [3].

In summary, while Lipitor is generally safe for long-term use, it is crucial to monitor liver function during treatment, especially for patients with pre-existing liver conditions or those taking high doses of the medication. Consult a healthcare professional for personalized advice regarding Lipitor and liver function maintenance.

Sources:
[1] <https://www.drugpatentwatch.com/p/tradename/LIPITOR>
[2] <https://www.ncbi.nlm.nih.gov/books/NBK548236/>
[3] <https://www.medicalnewstoday.com/articles/drugs-lipitor-side-effects>