See the DrugPatentWatch profile for cosentyx

Rapidly increasing the dose of Cosentyx (secukinumab) may lead to adverse effects due to the body's inability to adjust to the sudden change in medication levels. Although I cannot directly access databases or websites to provide real-time information, I can guide you on how to find such information and provide a general understanding based on the available context.

Cosentyx is a medication used to treat various conditions such as plaque psoriasis, psoriatic arthritis, and ankylosing spondylitis. It is a monoclonal antibody that targets interleukin-17A (IL-17A), a protein involved in inflammation.

When it comes to dosage adjustments, it is crucial to follow the prescribing information and consult a healthcare professional. Rapid dose increases may lead to unwanted side effects due to the following reasons:

1. Increased cytokine release: Rapidly increasing the dose may result in a sudden surge of cytokines, leading to inflammation and potential adverse effects.
2. Immunogenicity: Rapid dose changes can affect the immune system's response to the medication, potentially leading to reduced efficacy or increased side effects.
3. Safety concerns: Rapid dose increases may exacerbate existing side effects or introduce new ones, such as infections, reactions at the injection site, or allergic reactions.

It is essential to consult the prescribing information or consult a healthcare professional for specific information on Cosentyx dosage adjustments.

Sources:

1. Cosentyx (secukinumab) injection, for subcutaneous use [Prescribing Information]. (2021). Novartis Pharmaceuticals Corporation. https://www.novartis.us/sites/www.novartis.us/files/cosentyx.pdf
2. DrugPatentWatch. (2021). Cosentyx (secukinumab) Drug Profile. https://www.drugpatentwatch.com/drugs/cosentyx/